All lanes of Interstate 44 at mile marker 172 near Jerome are open. Route 63 at Westphalia has also re-opened after being closed due to flooding.
Missouri Department of Transportation officials say they are continuing to monitor high waters near Route 50 at Mount Sterling, but Route 50 remains open at this time.
More than 40 roads throughout the state, mostly in central Missouri, remain closed due to flooding.
Drivers are encouraged to check MoDOT's Traveler Information Map, located at http://www.modot.org/, or call the department's toll free number, 1-888-ASK-MODOT, to get updated information on road conditions.